Parameterization of physical properties of layered body structure into equivalent circuit model

Abstract Background This study presents a novel technique to develop an equivalent circuit model (ECM) for analyzing the responses of layered body structure transcutaneous electrical nerve stimulation (TENS) by parameterizing and geometrical properties.Many classical ECMs are non-parametric because difficulty in projecting intrapersonal variability physical properties into ECM. However, not considering hampers patient-specifically response TENS personal optimization parameter design. To overcome this limitation, we propose tissue property-based (TPB) approach direct parameterization thus enable quantify effects variability. Results The proposed method was first validated through vitro phantom studies then applied in-vivo analyze on forearm. TPB-ECM calculated impedance network forearm corresponding TENS. In addition, modelled good agreement with well-known that have been achieved empirically. Conclusions TPB uses parameterized components compared conventional ECMs, overcoming problem ECMs. Therefore, has potential widely-applicable analysis could provide impactful guidance